ONCO-ADJUNCT™ Pathway-4™
The ONCO-ADJUNCT™ Pathway System brings a thoughtful approach to cellular imbalances using Protisorb™ technology and terpene enrichment, which support absorption of bioactive polyphenols.
This product should only be used in consultation with your medical provider.
We encourage you to learn everything you can about the specific pathways affected in your individual case… and to work closely with your doctor and/or a licensed medical or health care provider to choose the optimal pathway combination to address your own cellular imbalances.
This product is not intended to replace treatments recommended to you by your doctor and/or a licensed medical or health care provider.
Pathway 4™
Promotes Immune Function & Cell Cycles*
ONCO-ADJUNCT™ Pathway 4™ is a nutritional supplement that combines Beta Glucans with three Protisorb™ bioactive polyphenols using brown rice as the scaffold.
Protisorb™ technology delivers molecular polyphenols such as Fisetin, EGCG, and Resveratrol to your body by using protein as the carrier. Without Protisorb™ technology they are not assimilated because they don’t dissolve.
- Protisorb™ Brown Rice-Fisetin Complex – May support Sirtuin, NRF2, and NFkB pathways.*
- Protisorb™ Brown Rice-EGCG Complex – May support cellular health by influencing optimal autophagy.*
- Protisorb™ Brown Rice trans-Resveratrol Complex – May support Sirtuin, NRF2, and NFkB pathways as well.*
- Beta Glucans – May support optimal function of immune system.* Our source for Beta-glucan, called PureMune™, activates all three parts of the immune system, not just the Dectin 1. The activation of the Complement Immune System is critically important for overall immune health.*
Taken together with Pathways 1™, 2™, and 3™, these substances help to modulate the healthy function of your cellular pathways to promote cellular health.*
Dosing Instructions: 2 capsules twice daily
More About the P4 Ingredients
Research shows that these substances provide various types of health support.
Fisetin:
- Stimulates the Sirtuin (SIRT1) pathway, enhancing cellular autophagy and promoting overall cellular health*
- Activates the NRF2 pathway, boosting cellular antioxidant response and protecting against oxidative stress*
- Modulates the NF-κB pathway, contributing to a balanced cellular response*
EGCG:
- Modulates the AMPK pathway, supporting cellular energy balance and metabolic health*
- Affects the NF-κB pathway, promoting a balanced cellular response*
- Influences the MAPK/ERK pathway, impacting cell cycle regulation and cellular health*
Trans-Resveratrol:
- Stimulates the Sirtuin (SIRT1) pathway, promoting cellular autophagy and overall cellular health*
- Activates the AMPK pathway, enhancing cellular energy balance and metabolic function*
- Regulates the NF-κB pathway, for a balanced cellular response*
Beta Glucan:
- Engages with immune cell receptors, such as Dectin-1, to support optimal immune cell function and immune response at a cellular level*
- Activates the complement system, strengthening immune cell communication and coordination*
- Stimulates the production of cytokines, modulating cellular immune response and promoting overall immune health*
In stock, ready to ship
Couldn't load pickup availability
Pickup available at 120 Northeast 26th Street
Usually ready in 4 hoursPairs well with
*Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration, and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Directions for Use
ONCO-ADJUNCT™ Pathway-4™
$68.00
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, within 24 hours on weekdays.
Shipping Information
Use this text to answer questions in as much detail as possible for your customers.
Customer Support
Use this text to answer questions in as much detail as possible for your customers.
FAQ’s
Use this text to answer questions in as much detail as possible for your customers.
Contact Us
Use this text to answer questions in as much detail as possible for your customers.
Ingredients
Protisorb™ Fisetin
Protisorb™ EGCG
Protisorb Resveratrol
Beta Glucans (PureMune™)
About The ONCO-ADJUNCT™ Pathway™ System
The ONCO-ADJUNCT™ Pathway system is a comprehensive line of nutritional supplements designed to support cellular health, enhance immune function, and promote optimal metabolic pathways.* This system consists of the following specialized formulations:
Each targets specific health concerns while working synergistically to optimize overall well-being.*
Frequently Asked Questions
What is Pathway 4™?
Pathway 4™ is a dietary supplement within the ONCO-ADJUNCT™ system of Pathways 1, 2, 3, and 4, designed to support immune function, cellular wellness, healthy cell cycles, antioxidant defenses, and whole-body resilience.* It combines Beta Glucans with three ProtiSorb™ bioactive polyphenols: fisetin, EGCG, and trans-resveratrol.
Is Pathway 4™ a cancer treatment?
No. Pathway 4™ is not intended to diagnose, treat, cure, or prevent cancer or any other disease. It is a dietary supplement designed to support normal immune function, cellular wellness, antioxidant defenses, and healthy cell cycle regulation.*
What does Pathway 4™ support?
Pathway 4™ is designed to support:
- Immune system function*
- Healthy cell cycles*
- Cellular wellness*
- Antioxidant defenses*
- Normal autophagy*
- Cellular resilience*
- Healthy aging pathways*
- Whole-body wellness*
What are the main ingredients in Pathway 4™?
The key ingredients in Pathway 4™ are:
- ProtiSorb™ Fisetin
- ProtiSorb™ EGCG
- ProtiSorb™ trans-resveratrol
- Beta Glucans (PureMune™)
What is the main reason to choose Pathway 4™?
Pathway 4™ is designed for adults seeking practitioner-guided support for immune function, healthy cell cycles, antioxidant defenses, normal autophagy, cellular wellness, and whole-body resilience.* Pathway 4™ combines Beta Glucans with three ProtiSorb™ bioactive polyphenols — fisetin, EGCG, and trans-resveratrol — for broad cellular and immune-supportive wellness benefits.*
What is ProtiSorb™ technology?
ProtiSorb™ technology is designed to support the absorption and bioavailability of difficult-to-absorb botanical compounds.* In Pathway 4™, ProtiSorb™ helps deliver fisetin, EGCG, and trans-resveratrol using a brown rice scaffold to support enhanced dispersion, uptake, and utilization.*
Why does absorption matter for Pathway 4™?
Many polyphenols are biologically valuable but hard for the body to absorb efficiently in standard forms. Pathway 4™ uses ProtiSorb™ technology to support better bioavailability of fisetin, EGCG, and trans-resveratrol, so the formula is focused on how well the body can use the ingredients — not just the milligram amount listed on the label.*
What are Beta Glucans?
Beta glucans are naturally occurring compounds found in certain foods and organisms, including yeast, mushrooms, oats, barley, and other sources. In Pathway 4™, Beta Glucans are included to support healthy immune system function and immune cell communication.*
What is PureMune™?
PureMune™ is the Beta Glucan source used in Pathway 4™. It is included to support healthy immune function, immune cell activity, and communication within the immune system.*
How do Beta Glucans support immune health?
Beta Glucans help support normal immune system function by interacting with immune cells and supporting healthy immune communications.* In Pathway 4™, Beta Glucans are included as foundational immune-support nutrients within the broader ONCO-ADJUNCT™ system.*
What is fisetin?
Fisetin is a plant-based flavonoid found naturally in foods such as strawberries, apples, persimmons, onions, and cucumbers. In Pathway 4™, fisetin is included to support cellular wellness, antioxidant response pathways, healthy aging, and normal cellular renewal processes.*
Why does Pathway 4™ include fisetin?
Pathway 4™ includes ProtiSorb™ Fisetin to support cellular resilience, antioxidant defenses, and healthy aging pathways.* Fisetin is commonly discussed for its role in supporting normal cellular cleanup and renewal processes, including autophagy.*
What is EGCG?
EGCG stands for epigallocatechin gallate, a well-known polyphenol found in green tea. In Pathway 4™, EGCG is included to support cellular wellness, antioxidant defenses, metabolic balance, and normal autophagy.*
Why does Pathway 4™ include EGCG?
Pathway 4™ includes ProtiSorb™ EGCG to help support normal cellular energy balance, antioxidant defenses, healthy cell signaling, and cellular renewal processes.* EGCG is one of the most studied green tea polyphenols and is used here as part of a practitioner-guided cellular wellness formula.*
What is trans-resveratrol?
Trans-resveratrol is the active form of resveratrol, a polyphenol found naturally in foods such as grapes, berries, peanuts, and Japanese knotweed. In Pathway 4™, trans-resveratrol is included to support cellular health, antioxidant defenses, healthy aging pathways, and metabolic wellness.*
Why does Pathway 4™ include trans-resveratrol?
Pathway 4™ includes ProtiSorb™ trans-resveratrol to support Sirtuin-related pathways, antioxidant response, metabolic balance, and cellular wellness.* It works alongside fisetin, EGCG, and Beta Glucans to provide broad support for immune and cellular resilience.*
What does "healthy cell cycle support" mean?
Healthy cell cycle support means helping the body maintain normal cellular processes involved in growth, renewal, repair, and replacement.* Pathway 4™ is designed to support normal cell cycle regulation as part of overall cellular wellness.* It is not intended to treat abnormal cell growth or any disease.
What is autophagy?
Autophagy is one of the body's normal cellular cleanup and recycling processes. Through autophagy, cells help remove and recycle worn-out or damaged components. Pathway 4™ includes polyphenols that support normal autophagy as part of cellular health and healthy aging.*
What are sirtuins?
Sirtuins are proteins involved in normal cellular regulation, metabolic signaling, stress response, and healthy aging pathways. Pathway 4™ includes fisetin and trans-resveratrol, which are commonly used to support sirtuin-related cellular wellness pathways.*
What is NRF2?
NRF2 is a cellular pathway involved in the body's natural antioxidant response. Pathway 4™ is designed to support NRF2-related antioxidant defenses as part of cellular resilience and whole-body wellness.*
What is NF-κB?
NF-κB is a cellular signaling pathway involved in normal immune and inflammatory responses. Pathway 4™ includes bioactive polyphenols that support healthy NF-κB signaling and a balanced cellular response.* It is not intended to treat inflammatory diseases or any disease.
What does "brown rice scaffold" mean?
A brown rice scaffold refers to the rice-based carrier used in Pathway 4™'s ProtiSorb™ complexes. This scaffold helps support efficient delivery and dispersion of bioactive polyphenols, including fisetin, EGCG, and trans-resveratrol.*
Is Pathway 4™ vegan or dairy-free?
Pathway 4™ uses ProtiSorb™ bioactive polyphenols with a brown rice scaffold, making it suitable if you follow a vegan diet, avoid dairy, or have dairy sensitivities.
Does Pathway 4™ contain hemp, cannabinoids, or THC?
Pathway 4™ is not a hemp, cannabinoid, or THC product. Its primary ingredients are ProtiSorb™ Fisetin, ProtiSorb™ EGCG, ProtiSorb™ trans-Resveratrol, and Beta Glucans.
How do I take Pathway 4™?
The label's suggested use and instructions on the Dosing Guideline for Pathway 4™ is 2 capsules twice daily with or without food, or as directed by your healthcare professional.
Should I start with a low dose?
Ask your healthcare practitioner whether a lower starting amount is appropriate for you.
Can Pathway 4™ be used with chemotherapy, radiation, immunotherapy, or other medical treatments?
Do not use Pathway 4™ with chemotherapy, radiation, immunotherapy, surgery, or any other medical treatment unless your oncology team or licensed healthcare practitioner approves. Pathway 4™ is a dietary supplement. It is not intended to replace oncology care, medication, surgery, chemotherapy, radiation, immunotherapy, or any prescribed treatment plan.
Should I tell my medical team about Pathway 4™?
Yes. Always tell your medical care team about every supplement you take, including Pathway 4™. This helps your care team evaluate possible interactions, timing concerns, immune considerations, antioxidant support, liver metabolism, blood-thinning concerns, and procedure-related considerations.
Can Pathway 4™ help with treatment side effects?
No. Pathway 4™ is not intended to treat, prevent, or reduce side effects of chemotherapy, radiation, immunotherapy, medications, surgery, or any medical treatment. If you're experiencing nausea, fatigue, appetite changes, mouth sores, digestive changes, neuropathy, pain, weight loss, or any treatment-related concern, contact your oncology team.
Can Pathway 4™ replace medication or medical care?
No. Pathway 4™ should not replace medication, medical care, surgery, radiation, chemotherapy, immunotherapy, medical nutrition therapy, or any treatment plan prescribed by your healthcare provider. It is intended to support wellness under practitioner guidance.*
Can I combine Pathway 4™ with Pathway 1™, Pathway 2™, Pathway 3™, or Pathway 3 Plus™?
The 4 Pathway™ products are designed to be used as a system. However, the system is designed for practitioner-guided use, so consult your provider to determine which products, serving sizes, and timing are most appropriate for your individual wellness plan.
Can I take Pathway 4™ with other immune-support supplements?
Ask your healthcare practitioner before combining Pathway 4™ with other immune-support products. This includes mushroom extracts, Beta Glucans, green tea extracts, resveratrol, fisetin, quercetin, curcumin, high-dose antioxidants, or other immune or inflammatory-balance formulas. Combining multiple products may create unnecessary overlap.
Can I take Pathway 4™ with prescription medications?
Talk with your healthcare practitioner or pharmacist before taking Pathway 4™ with prescription medications. This is especially important if you take medications for blood thinning, blood pressure, blood sugar, cholesterol, immune conditions, mood, sleep, pain, seizures, heart rhythm, liver metabolism, or kidney function.
Can I take Pathway 4™ before or after surgery?
Do not use Pathway 4™ before or after surgery unless your surgeon or healthcare practitioner approves it. Some supplements and botanicals may affect bleeding risk, blood pressure, blood sugar, anesthesia, immune response, or recovery timing.
Who should be especially cautious with Pathway 4™?
Talk with your healthcare practitioner before using Pathway 4™ if you:
- Take prescription medications
- Take blood-thinning medication
- Take blood pressure or blood sugar medication
- Take immune-related medications
- Are undergoing chemotherapy, radiation, immunotherapy, surgery, or other medical treatment
- Have autoimmune or immune-related concerns
- Have liver, kidney, digestive, bleeding, or cardiovascular concerns
- Are sensitive to green tea extract, resveratrol, fisetin, Beta Glucans, yeast, rice, or any ingredient in the formula
- Are pregnant, nursing, or trying to conceive
- Have any diagnosed medical condition
Can pregnant or nursing individuals use Pathway 4™?
Pathway 4™ is not recommended during pregnancy, nursing, or while trying to conceive unless specifically directed by a qualified healthcare practitioner.
Can children use Pathway 4™?
Pathway 4™ is intended for adult use unless otherwise directed by a qualified healthcare professional. Do not give Pathway 4™ to children without direct practitioner supervision.
Can I drive or operate equipment after taking Pathway 4™?
Pathway 4™ is not designed as a sedating product. Individual responses to supplements can vary.
What should I do if I feel uncomfortable after taking Pathway 4™?
Stop using Pathway 4™ and contact your healthcare practitioner if you experience unusual symptoms, digestive upset, dizziness, weakness, lightheadedness, rash, allergic reaction, or any new or concerning response. Seek urgent medical attention for severe allergic reaction, chest pain, fainting, severe weakness, confusion, trouble breathing, or other serious symptoms.
Is Pathway 4™ FDA-approved?
Dietary supplements are not FDA-approved in the same way prescription drugs are. Pathway 4™ is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease.
Required Disclaimer
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.