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The Pathway System

The ONCO-ADJUNCT™ Pathway System brings a thoughtful approach to cellular imbalances using LPS™ technology – the gold standard for absorption of bioactive polyphenols.

LPS™ technology delivers molecular polyphenols such as Fisetin, EGCG, and Resveratrol to your body by using protein as the carrier. Without LPS™ technology they are not assimilated because they don’t dissolve.

We encourage you to learn all that you can about the specific pathways affected in your individual case… and to work closely with your doctor or health coach to selectively select the ideal pathway combinations to achieve optimal cellular balance.

ONCO-ADJUNCT™ Pathway 4™

ONCO-ADJUNCT™ Pathway 4™ is a nutritional supplement that combines Beta Glucans with three LPS™ bioactive polyphenols using brown rice protein as the scaffold.

  1. LPS™ Brown Rice-Fisetin Complex: May support Sirtuin, NRF2, and NFKB pathways.*
  2. LPS™ Brown Rice-EGCG Complex: May support cellular health by influencing optimal autophagy.*
  3. LPS™ Brown Rice-Resveratrol Complex: May support Sirtuin, NRF2, and NFKB pathways as well.*
  4. Beta Glucans May support optimal function of immune cells.* Our source for Beta-glucan, PureMune™, activates all three parts of the immune system, not just the Dectin 1. The activation of the Complement Immune System is critically important for overall immune health.*

Taken together with Pathways 1™, 2™/2-Ferro™, and 3™ these substances help modulate the healthy function of your cellular pathways to promote cellular health.*

More About the P4 Ingredients

Research shows that these substances provide various types of health support.

  • Stimulates the Sirtuin (SIRT1) pathway, enhancing cellular autophagy and promoting overall cellular health*
  • Activates the NRF2 pathway, boosting cellular antioxidant response and protecting against oxidative stress*
  • Modulates the NF-κB pathway, contributing to a balanced inflammatory response within cells*


  • Modulates the AMPK pathway, supporting cellular energy balance and metabolic health*
  • Affects the NF-κB pathway, promoting a balanced inflammatory response at a cellular level*
  • Influences the MAPK/ERK pathway, impacting cell cycle regulation and cellular health*


  • Stimulates the Sirtuin (SIRT1) pathway, promoting cellular autophagy and overall cellular health*
  • Activates the AMPK pathway, enhancing cellular energy balance and metabolic function*
  • Regulates the NF-κB pathway, contributing to a balanced cellular inflammatory response*

Beta Glucan:

  • Engages with immune cell receptors, such as Dectin-1, to support optimal immune cell function and immune response at a cellular level*
  • Activates the complement system, strengthening immune cell communication and coordination*
  • Stimulates the production of cytokines, modulating cellular immune response and promoting overall immune health*


The ONCO-ADJUNCT™ family of products appears to be well-tolerated. We advise you to consult with your healthcare practitioners regarding any questions or concerns about using these products, and their appropriate dosing.

In general, you should talk to your doctor about all the supplements you take, or want to take, so they can determine possible interactions and make a medical judgement on your behalf.

Note: The FDA places strict limitations on what we are allowed to say about dietary supplements of any kind.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

*Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration, and are not intended to diagnose, treat, cure, or prevent any disease or health condition.


The Onco-Adjunct family of products appears to be well tolerated. We advise individuals to consult with their healthcare practitioners regarding any questions or concerns about using these products, and their appropriate dosing. We include a blood thinner warning on the Pathway 2 product as it has a blood thinning effect. This warning is for individuals currently using pharmaceutical blood thinners. Also, if you are undergoing chemotherapy, we recommend that you discontinue Pathway 2 during the chemo therapy unless specifically directed by your health care practitioner.

In general you should talk to your doctor about all the supplements you want to take or are taking so that they can determine possible interactions and make a medical judgement. The following interactions with curcumin have been discussed in the literature:
  1. Chemo therapeutic suppression was potentially found with curcumin and camptothecin, mechlorethamine, and doxorubicin. Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ. Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002;62(13):3868-3875. (PubMed)
  2. Curcumin affects the FXa node in the thrombin pathway. Any anti-coagulant therapy that acts directly on thrombin should be avoided (Hirudin, Argatroban, Bivalirudin, Dabigatran). Any Indirect or direct FXa inhibitors should be discussed with your doctor.

The FDA places strict limitations on what we are allowed to say about dietary supplements of any kind.

This is a very individual decision, and is based on your progress toward optimal health as demonstrated through the testing protocols of your health practitioner(s).

Your health care practitioner will have testing protocols that will be able to measure your health status.

The Company is coming out with a maintenance product containing Hemp, Frankincense and C60. This will be available later in the year.

We have recommended dosing on each label but recommend working with and following the advice of your own healthcare practitioner.

The application of the LPS™ technology to these botanicals (see # 17) enhances the ability of these molecules to absorb into your body.

Some people do experience an initial drowsiness with the Pathway 1™ tincture due to the presence of cannabinoids. We recommend ½ dose on days 1 through 3, taken at bedtime. Any drowsiness will diminish rapidly as your body adjusts. This effect does not apply to Pathway 2™ and Pathway 3™ products and they may be taken at recommended doses from day one.

Dietary supplements are regulated by the FDA in regard to manufacture and label claims, but are NOT ever approved by the FDA like pharmaceutical drugs are. Pathway™ products are manufactured in strict accordance with GMP (Good Manufacturing Practices) protocols in our own pharma manufacturing facility. Our facility has been inspected by the FDA.

We perform our own internal and third party testing on every ingredient which we use. Our testing includes heavy metal, pesticide and microbiology. Most of our ingredients are sourced from India and the Holy Land with some support ingredients coming from the US and Asia. We source from companies that work with local farmers who do NOT use pesticides or GMOs.

At our own FDA registered, GMP certified facility in the USA.

Yes, we welcome this interaction and are willing to speak with your healthcare practitioner via Zoom or phone appointment. Please set up an appointment by calling 405-694-4175 x7001.

ONCO-ADJUNCT™ Pathway 2-Ferro™ uses shellfish-free chondroitin as the scaffold for curcumin and quercetin, with synergetic frankincense.

Both Pathway 2™ and Pathways 2-Ferro™ contain LPS™ curcumin, LPS quercetin, and frankincense. The difference is that the shellfish-free chondroitin scaffold helps reduce overall cysteine intake in order to induce ferroptosis.

Natural cell clearing has to do with the natural death of an old or damaged cell. Curcumin and quercetin may help your body clear those cells to make room for newer cells by stimulating the p53 pathway.*

LPS™ is an acronym for ”Liquid Protein Scaffold,” which is now a patented technology. A group of researchers from Oklahoma Medical Research Foundation and the University of Oklahoma were exploring ways to take certain plant extracts that were very poorly absorbed in the gut and make them ultra-bioavailable. The first result was a molecular curcumin that was taken in capsule form. Tests were performed demonstrating exponential levels (never before seen) in the bloodstream and rapid, transformative results. We now apply LPS™ Technology to a variety of other botanicals so they may deliver maximum cellular support to humans and animals.

Always discuss your supplements with your doctor. Pathway™ products may be beneficial with low dose chemotherapy.*

Pathway 1™ was formulated to work hand-in-hand with chemotherapy.* No ingredient should interfere with the actions of chemotherapeutics. In fact, it may help improve your experience.*

On the other hand, we recommend you stay off Pathway 2™ on the days you have chemotherapy treatments, unless otherwise instructed by your doctor.

Pathway 1™ contains three ingredients that support different cellular pathways in our cells.* For example, hemp extract may support the PPAR-gamma pathway – an epigenetic pathway responsible for the healthy differentiation and division of cells.* Frankincense may support optimal cell proliferation by influencing the caspase pathway.*
Pathway 2™ contains three ingredients that may support cellular pathways responsible for the support of an optimal cell cycle, especially the p53 and NfKB pathways.*

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